3q6s
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The crystal structure of the heterochromatin protein 1 beta chromoshadow domain complexed with a peptide from Shugoshin 1
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Structural highlights
FunctionCBX1_HUMAN Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. Contents | ||||||||||||||||||
This page was last modified 10:46, 21 February 2024.