3r42
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Crystal structure of the yeast vps23 UEV domain in complex with a vps27 PSDP peptide
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Structural highlights
FunctionSTP22_YEAST Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association to the ESCRT-0 complex. Required for vacuolar targeting of temperature-sensitive plasma membrane proteins STE2 and CAN1.[1] [2] [3] See AlsoReferences
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This page was last modified 12:09, 14 March 2024.