Structural highlights
3s4t is a 8 chain structure with sequence from Polaromonas sp. JS666. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | X-ray diffraction, Resolution 1.9Å |
| Ligands: | ACT, CL, EPE, GOL, MSE, SO4 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
GRDC_POLSJ Involved in the gamma-resorcylate (2,6-dihydroxybenzoate) catabolism (Probable). Catalyzes the reversible decarboxylation of gamma-resorcylate to resorcinol (PubMed:29283551). Also catalyzes the decarboxylation of 2,3-dihydroxybenzoate to catechol, 2,4,6-trihydroxybenzoate to benzene-1,3,5-triol, and 2,6-dihydroxy-4-methylbenzoate to 5-methylbenzene-1,3-diol (PubMed:29283551).[1]
References
- ↑ Sheng X, Patskovsky Y, Vladimirova A, Bonanno JB, Almo SC, Himo F, Raushel FM. Mechanism and Structure of γ-Resorcylate Decarboxylase. Biochemistry. 2018 Jun 5;57(22):3167-3175. PMID:29283551 doi:10.1021/acs.biochem.7b01213
