3sai

Bacuills anthracis Dihydrofolate Reductase bound to propargyl-linked TMP analog, UCP1015

spinqualitylabelsall models 3sai, resolution 2.25Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3sai is a 2 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.25Å Ligands: 9DR, NAP, NI, PEG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q81R22_BACAN Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194] See Also Dihydrofolate reductase 3D structures

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