3sfm

Novel crystallization conditions for tandem variant R67 DHFR yields wild-type crystal structure

spinqualitylabelsall models 3sfm, resolution 1.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3sfm is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.4Å Ligands: MRD Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DYR21_ECOLX Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. See Also Dihydrofolate reductase 3D structures

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