3tg7
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Crystal structure of Adenovirus serotype 5 hexon at 1.6A resolution
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Structural highlights
FunctionCAPSH_ADE05 Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein (By similarity). Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus. See AlsoContents | ||||||||||||||||||
This page was last modified 13:27, 14 March 2024.