3tgn

Crystal Structure of the zinc-dependent MarR Family Transcriptional Regulator AdcR in the Zn(II)-bound State

spinqualitylabelsall models 3tgn, resolution 2.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3tgn is a 2 chain structure with sequence from Streptococcus pneumoniae D39. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2Å Ligands: ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ADCR_STRP2 Zinc-responsive regulator that acts both as a repressor and as an activator by regulating directly the promoters of its target genes. In the presence of zinc, directly represses the expression of the adcRCBA operon, of genes coding for a group of surface antigen zinc-binding pneumococcal histidine triad proteins (PhtA, PhtB, PhtD and PhtE), and of adcAII. Can also activate expression of adh.

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