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Structure of a M. tuberculosis salicylate synthase, MbtI, in complex with an inhibitor methylAMT
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Structural highlights
FunctionMBTI_MYCTU Mediates the production of salicylate from chorismate via an isochorismate intermediate. Presents both isochorismate synthase and isochorismate-pyruvate lyase activities. Salycilate is the starter unit in the production of the virulence-conferring salicylate-based siderophore mycobactin.[1] See AlsoReferences
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This page was last modified 10:35, 1 March 2024.