3vx8
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Crystal structure of Arabidopsis thaliana Atg7NTD-Atg3 complex
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Structural highlights
FunctionATG7_ARATH E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes. Involved in the senescence process.[1] See AlsoReferences
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This page was last modified 14:13, 18 October 2023.