3w0t

Human Glyoxalase I with an N-hydroxypyridone derivative inhibitor

spinqualitylabelsall models 3w0t, resolution 1.35Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3w0t is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.351Å Ligands: EPE, HPU, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function LGUL_HUMAN Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. See Also Glyoxalase 3D structures

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