3wx7

Crystal structure of COD

spinqualitylabelsall models 3wx7, resolution 1.35Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3wx7 is a 2 chain structure with sequence from Vibrio parahaemolyticus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.349Å Ligands: ACT, CA, GOL, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function A6P4T5_VIBPH Publication Abstract from PubMed The X-ray crystal structure of chitin oligosaccharide deacetylase from Vibrio parahaemolyticus (Vp-COD) was determined at an 1.35 A resolution. The amino acid sequence and structure of Vp-COD show that the enzyme comprises one polysaccharide deacetylase domain (PDD) and two carbohydrate-binding domains (CBDs). On the basis of a chitin-binding assay with Vp-COD and its CBDs-deleted mutant, it was confirmed that CBDs can adhere to chitin. The catalytic activity of the CBDs-deleted mutant was only mildly depressed compared with that of Vp-COD, indicating that CBDs are unlikely to affect the configuration of the active center residues in active site of PDD. Structure-based analysis of domain function of chitin oligosaccharide deacetylase from Vibrio parahaemolyticus.,Hirano T, Sugiyama K, Sakaki Y, Hakamata W, Park SY, Nishio T FEBS Lett. 2015 Jan 2;589(1):145-51. doi: 10.1016/j.febslet.2014.11.039. Epub, 2014 Dec 3. PMID:25479092 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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