4a46

Crosstalk between Cu(I) and Zn(II) homeostasis

spinqualitylabelsall models 4a46, resolution 1.85Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4a46 is a 4 chain structure with sequence from Synechocystis sp. PCC 6803. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.85Å Ligands: CL, NA, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function P73213_SYNY3 Publication Abstract from PubMed The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(II)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins. Crosstalk between Cu(I) and Zn(II) homeostasis via Atx1 and cognate domains.,Badarau A, Basle A, Firbank SJ, Dennison C Chem Commun (Camb). 2013 Sep 21;49(73):8000-2. doi: 10.1039/c3cc42709a. Epub 2013, Aug 7. PMID:23926594 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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