4c0j
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Crystal structure of Drosophila Miro EF hand and cGTPase domains in the apo state (Apo-MiroS)
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Structural highlights
FunctionMIRO_DROME Mitochondrial GTPase involved in mitochondrial trafficking. Milt and Miro form an essential protein complex that links Khc to mitochondria for light chain-independent, anterograde transport of mitochondria. Required for axonal transport to synapses within nerve terminals. Required presynaptically but not postsynaptically at neuromuscular junctions (NMJs).[1] [2] See AlsoReferences
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This page was last modified 07:18, 1 May 2024.