4e7r

Thrombin in complex with 3-amidinophenylalanine inhibitor

spinqualitylabelsall models 4e7r, resolution 2.25Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4e7r is a 6 chain structure with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.25Å Ligands: 0NW, GOL, NA, NAG, PO4, TYS Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function HIRV2_HIRME Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen. See Also Hirudin 3D structures Thrombin 3D Structures

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