4fbq

Crystal structure of a covalently fused Nbs1-Mre11 complex with two manganese ions per active site

spinqualitylabelsall models 4fbq, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4fbq is a 2 chain structure with sequence from Schizosaccharomyces pombe 972h-. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.5Å Ligands: MN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function RAD32_SCHPO Required for the repair of double strand breaks (DSB) caused by gamma and UV radiation. May work in conjunction with rhp51.NBS1_SCHPO Required for DNA damage repair and S-phase DNA damage checkpoint. Involved in telomere length maintenance and maintenance of chromatin structure.

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