4fjo
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Structure of the Rev1 CTD-Rev3/7-Pol kappa RIR complex
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Structural highlights
FunctionREV1_MOUSE Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.[1] See AlsoReferences
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This page was last modified 11:17, 1 March 2024.