4gac

High resolution structure of mouse aldehyde reductase (AKR1a4) in its apo-form

spinqualitylabelsall models 4gac, resolution 1.64Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4gac is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.64Å Ligands: EDO, FLC Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function AK1A1_MOUSE Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs (By similarity). See Also Alcohol dehydrogenase 3D structures Aldehyde dehydrogenase 3D structures

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