4gec
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Crystal Structure of E.coli MenH R124A Mutant
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Structural highlights
FunctionMENH_ECOLI Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro.[1] [2] References
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This page was last modified 11:28, 1 March 2024.