4glj
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Crystal structure of methylthioadenosine phosphorylase in complex with rhodamine B
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Structural highlights
FunctionC6KFA4_9BACT Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.[HAMAP-Rule:MF_01963] See AlsoContents | ||||||||||||||||||||
This page was last modified 15:50, 14 March 2024.