4gxy

RNA structure

spinqualitylabelsall models 4gxy, resolution 3.05Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4gxy is a 1 chain structure with sequence from Symbiobacterium thermophilum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.05Å Ligands: CCC, GTP, IRI, MG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed Coenzyme B(12) has a key role in various enzymatic reactions and controls expression of bacterial genes through riboswitches. Here we report the crystal structure of the Symbiobacterium thermophilum B(12) riboswitch bound to its ligand adenosylcobalamin. The riboswitch forms a unique junctional structure with a large ligand-binding pocket tailored for specific recognition of the adenosyl moiety and flanked by structural elements that stabilize the regulatory region and enable control of gene expression. Structural insights into ligand binding and gene expression control by an adenosylcobalamin riboswitch.,Peselis A, Serganov A Nat Struct Mol Biol. 2012 Nov;19(11):1182-4. doi: 10.1038/nsmb.2405. Epub 2012, Oct 14. PMID:23064646 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Riboswitch 3D structures

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