4i7z

Crystal structure of cytochrome b6f in DOPG, with disordered Rieske Iron-Sulfur Protein soluble domain

spinqualitylabelsall models 4i7z, resolution 2.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4i7z is a 8 chain structure with sequence from Mastigocladus laminosus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.803Å Ligands: 1E2, 8K6, BCR, CD, CLA, HEM, MYS, OCT, OZ2, UMQ Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CYB6_MASLA Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.[HAMAP-Rule:MF_00633] Publication Abstract from PubMed Cytochrome b6f catalyzes quinone redox reactions within photosynthetic membranes to generate a transmembrane proton electrochemical gradient for ATP synthesis. A key step involves the transfer of an electron from the [2Fe-2S] cluster of the iron-sulfur protein (ISP) extrinsic domain to the cytochrome f heme across a distance of 26 A, which is too large for competent electron transfer but could be bridged by translation-rotation of the ISP. Here we report the first crystallographic evidence of significant motion of the ISP extrinsic domain. It is inferred that extensive crystallographic disorder of the ISP extrinsic domain indicates conformational flexibility. The ISP disorder observed in this structure, in contrast to the largely ordered ISP structure observed in the b6f complex supplemented with neutral lipids, is attributed to electrostatic interactions arising from anionic lipids. Lipid-induced conformational changes within the cytochrome b6f complex of oxygenic photosynthesis.,Hasan SS, Stofleth JT, Yamashita E, Cramer WA Biochemistry. 2013 Apr 16;52(15):2649-54. doi: 10.1021/bi301638h. Epub 2013 Apr, 5. PMID:23514009 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Cytochrome b6

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