4k7r

Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation

spinqualitylabelsall models 4k7r, resolution 2.09Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4k7r is a 1 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.094Å Ligands: 3PK Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CUSC_ECOLI Part of a cation efflux system that mediates resistance to copper and silver. In pathogenic strains it allows the bacteria to invade brain microvascular endothelial cells (BMEC) thus allowing it to cross the blood-brain barrier and cause neonatal meningitis.

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