4ko4

High X-ray dose structure of anaerobically purified Dm. baculatum [NiFeSe]-hydrogenase after crystallization under air

spinqualitylabelsall models 4ko4, resolution 2.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4ko4 is a 4 chain structure with sequence from Desulfomicrobium baculatum and Desulfomicrobium baculatum DSM 4028. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2Å Ligands: CA, CL, FCO, GOL, H2S, NI, SE7, UOX Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PHSS_DESBA Publication Abstract from PubMed This study shows how the NiFeSe site of an anaerobically purified O2-resistant hydrogenase reacts with air to give a seleninate as the first product. Less oxidized states of the active site are readily reduced in the presence of X-rays. Reductive enzyme activation requires an efficient pathway for water escape. Structural foundations for the O2 resistance of Desulfomicrobium baculatum [NiFeSe]-hydrogenase.,Volbeda A, Amara P, Iannello M, De Lacey AL, Cavazza C, Fontecilla-Camps JC Chem Commun (Camb). 2013 Jul 11;49(63):7061-3. doi: 10.1039/c3cc43619e. PMID:23811828 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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