4kr7
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Crystal structure of a 4-thiouridine synthetase - RNA complex with bound ATP
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Structural highlights
FunctionTHII_THEMA Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity). Contents | ||||||||||||||||||||
This page was last modified 12:14, 1 March 2024.