4ksb

Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain

spinqualitylabelsall models 4ksb, resolution 3.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4ksb is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.8001Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function MDR1A_MOUSE Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

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