4kvg
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Crystal structure of RIAM RA-PH domains in complex with GTP bound Rap1
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Structural highlights
FunctionRAP1A_HUMAN Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. See AlsoContents | ||||||||||||||||||||
This page was last modified 12:15, 1 March 2024.