4l9d

Crystal structure of the PKD1 domain from Vibrio cholerae metalloprotease PrtV

spinqualitylabelsall models 4l9d, resolution 1.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4l9d is a 2 chain structure with sequence from Vibrio cholerae M66-2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.1Å Ligands: CA, CL, NA, PEG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PRTV_VIBCM Metalloprotease that exhibits a cytotoxic effect leading to cell death. In host tissues, it could play a role in pathogenesis by modulating the stability of the extracellular matrix components such as fibronectin and fibrinogen. Also able to cleave plasminogen.[UniProtKB:Q9KMU6]

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