4ld0
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T. thermophilus RuvC in complex with Holliday junction substrate
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Structural highlights
FunctionRUVC_THET8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). Contents | ||||||||||||||||||
This page was last modified 12:18, 1 March 2024.