4ldr
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Structure of the S283Y mutant of MRDI
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Structural highlights
FunctionMTNA_HUMAN Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.[1] References
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This page was last modified 12:19, 1 March 2024.