4lh6
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Crystal structure of a LigA inhibitor
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Structural highlights
FunctionDNLJ_ENTFA DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). See AlsoContents | ||||||||||||||||||||
This page was last modified 12:19, 1 March 2024.