4ly9

Human GKRP complexed to AMG-1694 [(2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorpholin-4-yl]methyl}-4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol] and sorbitol-6-phosphate

spinqualitylabelsall models 4ly9, resolution 2.35Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4ly9 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.35Å Ligands: 1YY, GOL, IOD, S6P, SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function GCKR_HUMAN Inhibits glucokinase by forming an inactive complex with this enzyme. See Also Glucokinase Regulatory Protein

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