4mj8

Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with polyamine

spinqualitylabelsall models 4mj8, resolution 2.04Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4mj8 is a 3 chain structure with sequence from Vibrio cholerae O1 biovar El Tor str. N16961. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.04Å Ligands: EOH, SPM Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ATDA_VIBCH Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine. It can use polyamines such as spermine and N(1)-acetylspermine, but not putrescine or cadaverine. See Also Spermidine/spermine N-acetyltransferase

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