4npl

Crystal structure of Zebrafish ALKBH5 in complex with alpha-ketoglutarate

spinqualitylabelsall models 4npl, resolution 1.65Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4npl is a 2 chain structure with sequence from Danio rerio. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.651Å Ligands: AKG, MN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ALKB5_DANRE Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m(6)A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Requires molecular oxygen, alpha-ketoglutarate and iron (By similarity). See Also Dioxygenase 3D structures

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