4omh
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Crystal structure of the bacterial diterpene cyclase COTB2 variant F149L
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Structural highlights
FunctionCOTB2_STRMJ Catalyzes the cyclization of the linear isoprenoid intermediate geranylgeranyl diphosphate to tricycclic cyclooctat-9-en-7-ol in the cyclooctatin biosynthesis pathway. Cyclooctatin is a potent inhibitor of lysophospholipase.[1] [2] References
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This page was last modified 12:40, 1 March 2024.