4p55

Crystal structure of DNA binding domain of K11 from KSHV

spinqualitylabelsall models 4p55, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4p55 is a 2 chain structure with sequence from Human herpesvirus 8 strain GK18. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.504Å Ligands: MSE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function VIRF2_HHV8P Plays a role in the inhibition of host immune response. Acts by interacting with host EIF2AK2/PKR and inhibiting its activation. In turn, EIF2AK2/PKR substrates including EIF2S1 or histone H2A are not phosphorylated.

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