4pxs

Human GKRP bound to AMG-0265 (N-[(R)-(2-CHLOROPHENYL){7-[4-(2-HYDROXYPROPAN-2-YL) PYRIDIN-2-YL]-1-BENZOTHIOPHEN-2-YL}METHYL]CYCLOPROPANESULFONAMIDE) and Sorbitol-6-phosphate

spinqualitylabelsall models 4pxs, resolution 2.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4pxs is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.6Å Ligands: 2Y6, GOL, IOD, S6P, SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function GCKR_HUMAN Inhibits glucokinase by forming an inactive complex with this enzyme. See Also Glucokinase Regulatory Protein

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