4qaf

Crystal structure of an engineered lipocalin (Anticalin) in complex with VEGF(8-109)

spinqualitylabelsall models 4qaf, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4qaf is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.8Å Ligands: ACT, OMA, SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function LCN1_HUMAN Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket. See Also Neutrophil gelatinase-associated lipocalin VEGF 3D Structures

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