4wfq
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Crystal structure of TFIIH subunit
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Structural highlights
FunctionSSL1_YEAST Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro. SSL1 is essential for translation initiation.[1] [2] References
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This page was last modified 09:01, 20 March 2024.