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Structure of PH1245, a cas1 from Pyrococcus horikoshii
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Structural highlights
FunctionCAS1_PYRHO CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. See AlsoContents | ||||||||||||||||||||
This page was last modified 07:31, 27 September 2023.