5bud
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Crystal structure of Candida albicans Rai1 in complex with pU5-Mn2+
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Structural highlights
FunctionDXO_CANAL Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping and pyrophosphohydrolase activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity). Contents | ||||||||||||||||||||
This page was last modified 12:18, 6 March 2024.