5fwc

Human Spectrin SH3 domain D48G, E7A, K60A

spinqualitylabelsall models 5fwc, resolution 1.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5fwc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.4Å Ligands: EDO, NH4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease SPTN1_HUMAN West syndrome. The disease is caused by mutations affecting the gene represented in this entry. Function SPTN1_HUMAN Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. See Also Spectrin 3D structures

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