Structural highlights
Function
CHI4_CRYJA Has endochitinase activity (PubMed:15725197). Hydrolyzes chitin oligosaccharides, GlcNAc(n), with different degrees of polymerization (n=2-6), a soluble substrate glycol chitin, and an insoluble substrate beta-chitin nanofiber in vitro. GlcNAc(6) is hydrolyzed at the second glycosidic linkage from the reducing end in addition to the middle linkage. GlcNAc(4) is further hydrolyzed to GlcNAc(2). Has antifungal activity against hyphal growth of H.rufa (PubMed:29756783).[1] [2]
See Also
References
- ↑ Fujimura T, Shigeta S, Suwa T, Kawamoto S, Aki T, Masubuchi M, Hayashi T, Hide M, Ono K. Molecular cloning of a class IV chitinase allergen from Japanese cedar (Cryptomeria japonica) pollen and competitive inhibition of its immunoglobulin E-binding capacity by latex C-serum. Clin Exp Allergy. 2005 Feb;35(2):234-43. PMID:15725197 doi:10.1111/j.1365-2222.2005.02167.x
- ↑ Takashima T, Numata T, Taira T, Fukamizo T, Ohnuma T. Structure and Enzymatic Properties of a Two-Domain Family GH19 Chitinase from Japanese Cedar ( Cryptomeria japonica) Pollen. J Agric Food Chem. 2018 Jun 6;66(22):5699-5706. PMID:29756783 doi:10.1021/acs.jafc.8b01140
