5hi6

The high resolution structure of dihydrofolate reductase from Yersinia pestis complex with methotrexate as closed form

spinqualitylabelsall models 5hi6, resolution 2.05Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5hi6 is a 2 chain structure with sequence from Yersinia pestis CO92. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.051Å Ligands: CA, CL, K, MSE, MTX Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function A0A3N4BLI0_YERPE Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[ARBA:ARBA00025067][PIRNR:PIRNR000194] See Also Dihydrofolate reductase 3D structures

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