5hvo

Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A

spinqualitylabelsall models 5hvo, resolution 2.47Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5hvo is a 4 chain structure with sequence from Aspergillus fumigatus Af293. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.467Å Ligands: UDP, VDM Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TPS1B_ASPFU Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process (PubMed:20439478). The disaccharide trehalose serves as a storage carbohydrate that is mobilized during conidial germination (PubMed:20439478). Regulates the level of trehalose as a protectant for cell integrity during thermal and oxidative stress (PubMed:20439478).

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