5khs
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Crystal structures of the Burkholderia multivorans hopanoid transporter HpnN
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Structural highlights
FunctionHPNN_BURM1 Essential for hopanoid transport from the cytoplasmic to the outer membrane (PubMed:28584102). Is capable of shuttling hopanoid lipids from the inner membrane to the periplasm, where they probably spontaneously insert to the inner leaflet of the outer membrane, strengthening the cell envelope (PubMed:28584102). May be a proton-motive-force (PMF)-dependent transporter (PubMed:28584102). Is critical for multidrug resistance and cell wall remodeling in Burkholderia (PubMed:28584102).[1] References
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This page was last modified 12:40, 6 March 2024.