5kkx
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Crystal structure of a TbpB C-lobe mutant from Neisseria meningitidis M982
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Structural highlights
FunctionTBPB1_NEIMI Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host. Acts as a TF receptor and is required for TF utilization. Involved in the initial capture of TF. Helps select only those TF molecules that can be used as an iron source and concentrates them on the cell surface, maintaining the iron-loaded status of the TF C-terminal lobe until its delivery to TbpA.[1] See AlsoReferences
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This page was last modified 10:02, 27 September 2023.