5lbn
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High-resolution crystal structure of the UBC core domain of UBE2E1/UbcH6
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Structural highlights
FunctionUB2E1_HUMAN Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination.[1] [2] See AlsoReferences
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This page was last modified 12:01, 9 May 2024.