5o9b

Solution NMR structure of human GATA2 C-terminal zinc finger domain

spinqualitylabelsall models 5o9b Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5o9b is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR Ligands: ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease GATA2_HUMAN Deafness-lymphedema-leukemia syndrome;Inherited acute myeloid leukemia;Myelodysplastic syndrome;Monocytopenia with susceptibility to infections. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Function GATA2_HUMAN Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.

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