5qip
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Covalent fragment group deposition -- Crystal Structure of OUTB2 in complex with PCM-0102153
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Structural highlights
FunctionOTUB2_HUMAN Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains.[1] [2] See AlsoReferences
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This page was last modified 12:24, 18 February 2026.