5uke

NMR structure of monomeric human IRAK-M Death Domain R56D, Y61E mutant

spinqualitylabelsall models 5uke Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5uke is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease IRAK3_HUMAN Disease susceptibility is associated with variations affecting the gene represented in this entry. Function IRAK3_HUMAN Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.[UniProtKB:Q8K4B2] See Also Interleukin-1 receptor-associated kinase

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